The San Francisco 49ers entered 2025 battling the same demon that haunted them last season, injuries. A year after the injury bug derailed their campaign, the Niners have somehow managed to grind through the setbacks and sit at 4-2 after six games.

The San Francisco 49ers have dealt with a barrage of injuries in the first half of the season, but they are finally getting one of their best players back at full health. Star tight end George Kittle has been activated off of injured reserved ahead of the team's Week 7 game against the Atlanta Falcons.

San Francisco 49ers tight end George Kittle was activated from injured reserve Saturday after missing five games due to a hamstring injury. Defensive tackle Kevin Givens (pectoral) also was activated from the IR ahead of the Sunday night home game against the Atlanta Falcons.

The Seattle Seahawks and San Francisco 49ers face off in Week 1 of the NFL season today. Here's where to watch and start time.

George Kittle looks likely to make his San Francisco 49ers return and feature in Week 7 against the Atlanta Falcons. It’s finally some good news after the tight end was placed on injured reserve in Week 1. Six games later, Kittle’s return couldn’t come at a better time for the 49ers’ offense.

Seattle’s defensive goal was to crowd the line of scrimmage, taking away the outside zone run. The antidote to that is swing passes and Texas routes to McCaffrey out of the backfield, and Brock Purdy took that option again and again and again Sunday.

NFL sources see the 49ers, Rams, Seahawks, Bills, Patriots, Jaguars, and Eagles as trade deadline buyers. More at Pro Football Rumors.

The San Francisco 49ers suffered a loss to the Tampa Bay Buccaneers during Week 6 of the season, enduring injuries throughout the roster. As the 49ers gear up f

George Kittle has missed the last five games due to a hamstring injury he sustained in the San Francisco 49ers' season-opener against the Seattle Seahawks.