Previous captain Jamie George has been ruled out of Englands first Six Nations; The England squad has been hit by five injuries including Georges after the weekends club matches and new players have been called up;

England have suffered significant injury news ahead of the Six Nations with Jamie George ruled out of their opening fixtures against Ireland and France.Hooker George, who has been replaced by Maro Itoje as captain,

England head coach Steve Borthwick has been forced to call up five players after his Six Nations squad was rocked by injury on a damaging weekend of club rugby.

First-choice scrum-half Alex Mitchell, who missed the autumn Tests with a neck injury, could also miss the game with a knee problem he picked up against Munster on Friday

England have been dealt a fresh blow ahead of their Six Nations opener against Ireland with news that vice-captain Jamie George will miss the game in Dublin. The hooker suffered a hamstring injury in Saracens’ Investec Champions Cup defeat by Castres on Sunday and will miss the start of the tournament, the Rugby Football Union has confirmed.

Jamie George, replaced as England captain by Maro Itoje last week, has been ruled out of their Six Nations opener against Ireland, with scrumhalf Alex Mitchell also a doubt after the squad was hit by a raft of injuries.

Hooker Jamie George will miss England's Six Nations opener against Ireland while scrum-half Alex Mitchell is a doubt with a knee problem.